Recently I upgraded my laptop to Mac OSX Big Sur and it has been a Mouse Nightmare with my Logitec MX Master 2S Mouse
I went to the Logitech Support website and referenced the following link regarding Big Sur Problems
After upgrading the Logitec drivers, the issue persisted.
I found the following solution that helped to reset the Mouse settings
$ mkdir $HOME/backups
$ find $HOME/Library/Preferences -type f -iname "*mouse*" -exec mv -f {} $HOME/backups \;
$ reboot
But the main problem in my case, was that I was connecting my mouse to my MACBook laptop thru a USB extender.
The MACBook Pro only has 2 USB ports.
I purchased a 5 port USB extender I was using for all devices and I had the Logitec Bluetooth Adapter plugged into the USB Extender; apparently this causes latency.
As a matter of troubleshooting I removed all USB devices and plugged only the Logitec Bluetooth Device in and the mouse worked perfectly.
Because I needed the ports, I paired the mouse with the native Bluetooth, and now all is well in Mouse Madness Universe!